GUILLAIN-BARRE SYNDROME
GUILLAIN-BARRE SYNDROME OR INFECTIOUS POLYNEURITIS – Etiology, Pathophysiology, Signs and Symptoms, Diagnostic Evaluation and Management Guillain-Barre Syndrome (GBS) is a acute condition that involves progressive muscle weakness or paralysis. It is an autoimmune disorder in which the body’s immune system attacks its own nervous system, causing inflammation that damages the myelin sheath of the nerve. This damage (demyleinazation) slows or stops the conduction of impulses through the nerve. The impairment of nerve impulses to the muscles leads to symptoms that may include muscle weakness, paralysis, spasms, numbness, tingling or pin-and-needle sensations and tenderness. ETIOLOGY Camphylobacter jejuni infection: camphylobacter infection is also the most common risk factor for Guillain-Barre. It is often found in undercooked food, especially poultry. Influenza Cytomegalovirus Epstein-Barr virus infection Mycoplasma pneumonia HIV or AIDS PATHOPHYSIOLOGY A condition of symptoms characteriz...